These results from the team of Jean-Luc Balligand (WELBIO – IREC - UCLouvain) pave the way for the development of more potent molecules to block aquaporin and treat heart failure more efficiently.
This jammer prevents proper regulation of sugar, causing insulin resistance in people with diabetes. Patrice Cani (UCLouvain) and Claude Knauf (INSERM) also discover that a lipid produced by our body helps preventing this dysfunction.
François Fuks (WELBIO – ULB) and his colleagues show the key role of a chemically modified RNA letter, hydroxymethylcytosine (hmC), during the differentiation of embryonic stem cells.
Sophie Lucas (WELBIO – UCLouvain) and her team neutralize a molecule that blocks immune responses against cancer. This novel form of immunotherapy induces tumor regressions by strongly increasing the efficacy of another well-known immunotherapy.
The Human Molecular Genetics laboratory headed by Miikka Vikkula (WELBIO – UCLouvain) identified a gene responsible for primary lymphedema, a discovery essential for proper diagnosis and opening possibilities for the development of treatments.
Researchers led by Cédric Blanpain (WELBIO – ULB) identify for the first time the mechanisms by which cell-cell communication control the fate of mammary and prostate stem cells.
Cédric Blanpain (WELBIO - ULB) et son équipe identifient pour la première fois la manière dont l’étirement active les cellules souches de la peau pour induire l’expansion tissulaire.
Information on our projects portfolio, WELBIO investigators, their publications and the awards they received as well as technology transfer progresses.
Anna Maria Marini et Mélanie Boeckstaens (ULB) with teams from Strathclyde and Dundee show that the AmtB protein from the bacteria E. coli separately translocates ammonia and the proton, the ion being carried out by two chains of water molecules.
A team led by Jean-François Collet (WELBIO investigator at UCLouvain), offers an unprecedented perspective on the defense mechanisms of bacteria, contributing to the global effort to respond to antibiotic resistance.
Cédric Blanpain (ULB) and his team uncover the mechanisms mediating postnatal tissue development. They found that a unique developmental stem cell population mediates tissue expansion by a constant self-duplication throughout postnatal development.