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Publication in Cell

Mechanisms responsible for tissue growth

Developmental progenitors control the optimality of postnatal

Cédric Blanpain (ULB) and his team uncover the mechanisms mediating postnatal tissue development. They found that a unique developmental stem cell population mediates tissue expansion by a constant self-duplication throughout postnatal development.

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Publication in Nature

A better understanding of embryonic development

Isabelle Migeotte (WELBIO 2015-2019 - ULB) and her colleagues clarify a key stage of embryonic development. This data is essential for improving the production of synthetic embryos and limit the use of animal embryos.

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Publication in Nature Communications

Type 1 diabetes: how interferon-α impacts human pancreatic β-cells

Decio L. Eizirik (WELBIO - ULB) and colleagues used a multi-omics approach to clarify the impact of interferon-α on human beta cells.

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Publication in Nature Reviews Endocrinology

Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure

In a recent review paper, Decio L. Eizirik (WELBIO investigator at ULB) and colleagues discuss the mechanisms leading to pancreatic beta cell failure in diabetes.

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COVID-19 : Research & Innovation

COVID-19 : research, innovation and expertise in Wallonia and Brussels

Find on a dedicated wesite all the projects set up at ULiège and in many other organisations in the Wallonia-Brussels Federation to fight against the virus and its consequences on health, society and the economy.

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Publication dans Nature Chemical Biology

Tel un funambule en équilibre, ppGpp - le ‘Magic spot’ - contrôle son propre destin

La régulation de la réponse stringente des bactéries par les alarmone

L’équipe d’Abel Garcia-Pino (investigateur WELBIO – ULB) et ses collègues des universités de Hasselt et d’Umeå, percent les mystères de la régulation de la réponse stringente des bactéries par les alarmones.

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Publication dans PLoS Genetics

Comment le transport de l’ion ammonium induit la filamentation des levures

Un transport assuré par les protéines de la famille Mep-Amt-Rh, comprenant les facteurs Rhésus humains

Une équipe de chercheurs menée par Anna Maria Marini (WELBIO / FNRS / ULB) décrit le mécanisme moléculaire par lequel les transcepteurs Mep2 de la levure induisent la filamentation en transportant l’ammonium au travers de la membrane cellulaire.

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First patients successfully treated

An anti-diabetes therapy for treating severe infections in a rare disease

Congenital neutropenia

First patients suffering from a rare disease named Glycogen Storage Disease 1B have been successfully treated with an anti-diabetes therapy. This study is led by Maria Veiga-da-Cunha (senior research associate FRS-FNRS at UCLouvain) and Emile Van Schaftingen (WELBIO investigator at UCLouvain). The results have been published in Blood. For the first time in a WELBIO project, investigators make a successful step from basic research to actual patient treatment.

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Diabète de type 1

Un long ARN non codant régule l’inflammation des cellules beta du pancréas

Une étude publiée dans PNAS

Les équipes de Decio E. Eizirik et de Izortze Santin décrivent le mécanisme moléculaire par lequel  un long ARN non codant spécifique régule l’inflammation des cellules beta du pancréas et contribue à la pathogenèse du diabète de type 1.

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