Novel biochemical aspects of neurodegeneration in Parkinson’s disease

neurological diseases • biochemistry • metabolism

Guido Bommer is Research Associate at the FNRS and professor at the Université catholique de Louvain. With his research group at the de Duve Institute, he studies the role enzymes, the function of which is still unknown, might play in cancer metabolism. Unexpected results regularly lead Guido Bommer to look at other diseases.

His WELBIO project is focused on Parkinson’s disease (PD), specifically on an enzyme that is potentially involved in both cancer and Parkinson’s disease. The project aims to investigate how this enzyme protects cells from stress, and how metabolic damage might link metabolic activity with protein aggregation and sensitivity to oxidative stress observed in PD.

This study may have a significant impact on our understanding of the pathogenesis of Parkinson’s disease and might reveal new therapeutic targets.

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